Overdose symptoms may include irregular heartbeats, severe dizziness, or fainting. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug . Common interactions include anxiety among females and diarrhoea among males. Its main use until now has been in the management of hypertension and angina. It is created by eHealthMe based on reports of 11 people who take Marijuana and Nifedipine from the FDA, and is updated regularly. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. nifedipine oral brand names and other generic formulations include: Adalat CC Oral, Adalat Oral, Afeditab CR Oral, Nifediac CC Oral, Nifedical XL Oral . Found inside – Page 488nicotinamide , interactions with AEDs carbamazepine ( CBZ ) 143 primidone ( PRM ) 162 nicotinic receptor 30 nifedipine , interactions with AEDs ... The phase IV clinical study analyzes what interactions people who take Marijuana and Nifedipine have. Your healthcare provider may need to adjust your dose of these medications to prevent interactions from occurring. Drug Name Generic Name : nifedipine Brand Name: Adalat, Adalat CC, Adalat XL (CAN), Apo-Nifed (CAN), Apo-Nifed AP (CAN), Nifedical XL, Novo-Nifedin (CAN), Procardia, Procardia XL Classification: Calcium channel-blocker, Antianginal, Antihypertensive Pregnancy Category C Dosage & Route Available forms : ER tablets—30, 60, 90 mg; capsules—10, 20 mg ADULTS Initial dose, 10 mg tid PO . Grapefruit may interact with nifedipine and lead to unwanted side effects. Found inside – Page 333Possible nifedipine toxicity ( decreased metabolism ) SK Bowles et al , Evaluation of the pharmacokinetic and pharmacodynamic interaction between quinidine ... Consult your healthcare professional (e.g., doctor or pharmacist) for . The interaction with high dose fentanyl appears to be due to the combination of nifedipine and a beta blocker, but the possibility that it may occur with nifedipine alone, with low doses of fentanyl, in other surgical procedures, or with other narcotic analgesics cannot be ruled out. may cause elevated liver function tests. We would like to show you a description here but the site won't allow us. Your doctor may change your treatment plan if you also use: Older adults may be more sensitive to the effects of this medicine. These drugs are known to inhibit CYP3A4. See additional information. Medicines that are known to inhibit or induce CYP3A4 may therefore alter the first-pass or the clearance of nifedipine. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Coumadin, Dilantin, and Prograf are just a few of the drugs that can interact with nifedipine. You should not use nifedipine if you are allergic to it. Alcohol. The immediate-acting form of nifedipine is also used to treat coronary spasm, the . For the long-term treatment of hypertension, only the extended-release formulations of nifedipine should be used. Found inside – Page 176In vitro, the concentrations of verapamil (Abbott Laboratories, Kent) and nifedipine (Bayer Pharmaceuticals Ltd, Berkshire) required to inhibit platelet ... The phase IV clinical study analyzes what interactions people who take Nifedipine and Prednisone have. Other drugs that have the same active ingredients (e.g. Nifedipine has mild interactions with at least 132 different drugs. Nifedipine may also be used for purposes not listed in this medication guide. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant, Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. The use of the eHealthMe site and its content is at your own risk. I take nifedipine. Found inside – Page 12-172 Nifedipine - Ethanol Summary : Concurrent nifedipine and ethanol administration resulted in an increase in nifedipine area - under - curve . This present volume is classified into two major parts; firstly, pharmacoki netic drug interactions and, secondly, pharmacodynamic drug interactions. Found inside – Page 327Nifedipine, however, did not reduce the contractile effects of NPY on human mesenteric veins, indicating some selectivity of action /33/. Purpose: The drug-drug interactions (DDIs) of tacrolimus greatly contributed to pharmacokinetic variability. Group I animals were treated with nifedipine (2.5 mg/kg body weight, p.o.) Common interactions include fatigue among females and haemoglobin decreased among males. Pharmacokinetics When used in preterm labor, it relaxes the uterine wall muscle, decreasing contractions and prolonging the time to delivery. It is created by eHealthMe based on reports of 1,499 people who take . melatonin oral decreases effects of nifedipine oral by pharmacodynamic antagonism. Nifedipine interaction Download PDF. Found inside – Page 39this Netfinavir Mesylate ( CoNorgestrel ( Data indicates that nife- excluded ; a dosage adjustment of Pred Forte Ophthalmic administration of nifedipine ... It is created by eHealthMe based on reports of 39,833 people who have side effects when taking Nifedipine from the FDA, and is updated . The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Found inside – Page 48551 on Drug - drug interactions : effect of quinidine on nifedipine Metabolism of the 1 : 177-87 for the separation of isradipine and its main metabolites ... All generic drug interactions for nifedipine oral (lists will include brand and generic names): 23 serious drug interactions. The interaction with high dose fentanyl appears to be due to the combination of nifedipine and a beta blocker, but the possibility that it may occur with nifedipine alone, with low doses of fentanyl, in other surgical procedures, or with other narcotic analgesics cannot be ruled out. You may need to stop using the medicine at least 36 hours before surgery. Alfuzosin. generic drugs) are not considered. Found inside – Page 949DRUG AND SUPPLEMENT INTERACTIONS A human trial indicated that nifedipine with ginger had a greater antiplatelet action than nifedipine alone (Young et ... simvastatin is now contraindicated with ciclosporin, danazol and gemfibrozil. Therefore, before using this product, tell your doctor or pharmacist of all . Alcohol interaction is found among people who take Nifedipine, especially for people who are female, 50-59 old. Nifedipine capsules or tablets may contain lactose. Some reports may have incomplete information. Use the medicine exactly as directed. The phase IV clinical study analyzes what interactions people who take Metoprolol tartrate and Nifedipine have. Both nifedipine and alcohol can increase the risk of hypotension. Both nifedipine and acebutolol can increase the risk of hypotension. Angina and heart failure possible with β-blockers. 202 minor drug interactions. You should not breastfeed while using nifedipine. By subscribing you agree to the Terms of Use and Privacy Policy. Found inside – Page 1082.6.2 Effects of HGJ on nifedipine pharmacokinetics It was shown that HGJ ... that evaluation using rats is useful for predicting drug-food interactions. There are 9 disease interactions with nifedipine: Aortic stenosis. Found inside – Page 58Nifedipine exaggerated the ethanolinduced motor incoordination . A similar interaction is expected between ethanol and other calcium channel blocking agents ... As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload. Antihypertensives may potentiate hypotensive effects. Get up slowly and steady yourself to prevent a fall. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. The interaction with high dose fentanyl appears to be due to the combination of nifedipine and a beta-blocker, but the possibility that it may occur with nifedipine alone, with low doses of fentanyl, in other surgical procedures, or with other narcotic analgesics cannot be ruled out. home > drug interactions checker > melatonin oral and nifedipine oral interactions. Found inside – Page 41Side effects and pharmacodynamic interaction . In Krebs , R. ( ed ) Treatment of Cardiovascular Diseases by Adalat ( Nifedipine ) , pp . 270–314 . Use all your heart or blood pressure medications as directed and read all medication guides you receive. Found inside – Page 2891-3,11 DRUG INTERACTIONS Nifedipine : Concomitant administration of melatonin and nifedipine has resulted in elevations in blood pressure and heart rate . DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Found inside – Page 100The drugs listed above have reported interactions with nifedipine. Not all of these interactions may have been reported for the other, newer calcium channel ... Found inside – Page 84Peripheral edema due to nifedipine itraconazole interaction : a case report . Arch Dermatol 1996 ; 132 : 350 . 170. Bailey DG , Spence JD , Munoz C , et al ... Mylan-Nifedipine Extended Release: Nifedipine belongs to the class of medications called calcium channel blockers. An interaction is when a substance changes the way a drug works. [ ABPI, 2017b; Joint Formulary Committee, 2019] Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. Avoid medication errors by using only the form and strength your doctor prescribes. Health Topics Symptoms and Signs Supplements Medications Slideshows Images Quizzes. Nifedipine is a calcium channel blocker in the dihydropyridine subclass. © 1996-2021 Everyday Health, Inc. The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. A short summary of this paper. Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Consequently, in ethyl acetate, the growth rate of these lateral surfaces was slowed down, leading to the appearance of long-and-thin . Nifedipine belongs to a class of medications known as calcium channel blockers. Dosage of drugs is not considered in the study. Found inside – Page 128Interacting Members Calcium Channel Blockers Interacting Members : Amlodipine ; Bepridil ; Diltiazem ; Felodipine ; Isradipine ; NICARdipine ; NIFEdipine * ... It is created by eHealthMe based on reports of 2,277 people who take Nifedipine and Clonidine from the FDA, and is updated regularly. Nifedipine has the following interaction information: Acebutolol. Future clinical research should focus on large placebo-controlled trials, powered for perinatal outcomes. All generic drug interactions for nifedipine oral (lists will include brand and generic names): 23 serious drug interactions. Procardia (nifedipine) is a calcium channel blocker (CCB) used to treat and prevent angina (heart pain) and high blood pressure (hypertension). may cause arrhythmias. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Drug Information on Adalat, Adalat CC, Afeditab CR (nifedipine) includes side effects, uses, drug interactions, dosage, drug pictures, overdose symptoms, and what to avoid. The phase IV clinical study analyzes what interactions people who take Nifedipine and Clonidine have. Found inside – Page 15Products include : Amoxapine ( Enhanced activity of nifedipine and beta blocker may ... analFood Interactions ( Potential for severe hypotension gesic ) . You should not eat grapefruit or drink grapefruit juice while you taking this medicine. Newsletter Article; Published: 27 January 2013; Nifedipine interaction. Reactions Weekly volume 288, page 10 (1990 . Nifedipine is not approved for use by anyone younger than 18 years old. Drug interactions are reported among people who take Metoprolol tartrate and Nifedipine. 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